This is a pretty cool little tutorial for using a CSS Framework. Check it out.
Design A Fresh Blog Theme On The 960 Grid | My Ink Blog:
"Up until a couple of weeks ago I never really understood the fascination with using CSS frameworks in web design. They just seemed very limiting and boring. Then I used one. My whole perspective on their usefulness has done a complete 180. I can thank Jeffrey Way for convincing me to give the 960 framework a try, after I read/listened to his post: A Detailed Look at the 960 CSS Framework.
If you have been hesitant to give CSS frameworks a try for similar reasons, I suggest you at least give them a fair shake before you write them off completely. I’m not saying they are for everyone, but most of the excuses for not trying them don’t hold any weight."