If what you’re photographing has been photographed a lot, if it’s a cliché, then you better do all the more research to ensure that your version won’t be just another iteration on the heap. Strive to tell a unique story in spite of how trodden your topic is. (Unique diseases don’t make for unique stories, as one example.)
"It’s hard to know how big your tray will be. The scope of the story and the number of threads you’ve created determines the range of the images. Try not to do too tight an edit at each pass through your pictures. Each time, just ask, does this image meet a higher standard than the rest of the pictures. Then go through them again and raise the standard. If you have two equally good pictures of the same thing but they convey different qualities, then keep them both; if they say the same thing, chose one."
Great article linked from APE today.